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Clinical Gaseous Microemboli Assessment of an Oxygenator with Integral Arterial Filter in the Pediatric Population

Preston TJ, Gomez D, Olshove VF, Phillips A, Galantowicz

Clinical Gaseous Microemboli Assessment of an Oxygenator with Integral Arterial Filter in the Pediatric Population 

The use of an arterial line filter (ALF) within the pediatriccardiopulmonary bypass (CPB) circuit is not a new concept.It has always presented the perfusionist with a circuit componentthat while valuable, increased prime volume. The purpose of thisstudy was to evaluate the change in prime volume and embolibetween a conventional oxygenator with separate ALF and a newgeneration oxygenator with integral arterial filter (AF). We performeda clinical, non-randomized retrospective evaluation of theTerumo Capiox ® RX15 (Terumo Cardiovascular Systems Corporation,Ann Arbor, MI) ( n = 10) in conjunction with the TerumoCapiox ® AF125X ALF or the Capiox ® AF02 vs. the TerumoCapiox ® FX15 oxygenator with integral AF ( n = 10). The abovecircuit components, in combination with the LUNA EDAC ®(emboli detection and classification) Quantifier (LUNA Innovations,Blacksburg, VA) were placed at various locations withineach patient?s CPB circuit to establish and quantify the presenceand volume of gaseous emboli during all phases of cardiopulmonarybypass. The EDAC ® system is available/used for all patientsundergoing CPB at this institution. When compared to a moreconventional CPB circuit, the Capiox ® FX15 primes more easilyas it does not require a carbon dioxide flush while still providinga 32 ? AF. There was no statistical difference in air handlingbetween the tested oxygenators and their associated circuits.During this review it was determined that use of the Capiox ®FX15 simplifies the arterial limb of the pediatric CPB circuit.Removal of the separate ALF led to the removal of several, nowunnecessary, arterial connectors and additional tubing (arterialline filter bypass). Removal of these components led to a reductionin prime volume and decreased the hemodilutional effect.The FX15 provided a safe, simplified pediatric CPB circuitand was as effective in gaseous microemboli removal as was themore traditional RX15 with separate ALF during this review

Reference: Preston TJ, Gomez D, Olshove VF, Phillips A, Galantowicz. Clinical Gaseous Microemboli Assessment of an Oxygenator with Integral Arterial Filter in the Pediatric Population.  JECT 2009;41:226-230. 

Institution(s): The Heart Center at Nationwide Dhildren's Hospital Columbus OH, Ohio State University, Columbus OH

Category: abstract

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